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Simulating the Catalytic Effect of a Designed Mononuclear Zinc Metalloenzyme that Catalyzes the Hydrolysis of Phosphate Triesters

[Image: see text] One of the greatest challenges in biotechnology and in biochemistry is the ability to design efficient enzymes. In fact, such an ability would be one of the most convincing manifestations of a full understanding of the origin of enzyme catalysis. Despite some progress on this front...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Singh, Manoj Kumar, Chu, Zhen T., Warshel, Arieh
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207531/
https://ncbi.nlm.nih.gov/pubmed/25233046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp507592g
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