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The Role of GluN2A and GluN2B Subunits on the Effects of NMDA Receptor Antagonists in Modeling Schizophrenia and Treating Refractory Depression

Paradoxically, N-methyl-D-aspartate (NMDA) receptor antagonists are used to model certain aspects of schizophrenia as well as to treat refractory depression. However, the role of different subunits of the NMDA receptor in both conditions is poorly understood. Here we used biochemical and behavioral...

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Detalhes bibliográficos
Main Authors: Jiménez-Sánchez, Laura, Campa, Leticia, Auberson, Yves P, Adell, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207347/
https://ncbi.nlm.nih.gov/pubmed/24871546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.123
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