Adjusting Glucose-Stimulated Insulin Secretion for Adipose Insulin Resistance: An Index of β-Cell Function in Obese Adults

OBJECTIVE: The hyperbolic relationship between insulin secretion and sensitivity has been used to assess in vivo β-cell function (i.e., the disposition index). The disposition index emphasizes the importance of taking into account both skeletal muscle and hepatic insulin resistance to depict insulin...

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Bibliographic Details
Main Authors: Malin, Steven K., Kashyap, Sangeeta R., Hammel, Jeff, Miyazaki, Yoshi, DeFronzo, Ralph A., Kirwan, John P.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2014
Subjects:
Clinical Care/Education/Nutrition/Psychosocial Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207203/
https://ncbi.nlm.nih.gov/pubmed/25139885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc13-3011
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