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Sildenafil Inhibits Advanced Glycation End Products-induced sFlt-1 Release Through Upregulation of Heme Oxygenase-1

OBJECTIVES: We examined the effect of sildenafil citrate on advanced glycation end products (AGEs)-induced soluble fms-like tyrosine kinase 1 (sFlt-1) release in JEG-3 choriocarcinoma cells. METHODS: Cells were incubated with control bovine serum albumin (BSA) or AGEs-BSA, and expression of sFlt-1 m...

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Autori principali: Jeong, Jae Hyeok, Kim, Hwi Gon, Choi, Ook Hwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Society of Menopause 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207003/
https://ncbi.nlm.nih.gov/pubmed/25371895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6118/jmm.2014.20.2.57
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