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Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase‐1

Despite advances in our understanding of the oxidative pathways mediated by free hemoglobin (Hb), the precise contribution of its highly reactive redox forms to tissue and organ toxicities remains ambiguous. Heme, a key degradation byproduct of Hb oxidation, has recently been recognized as a damage‐...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Kassa, Tigist, Jana, Sirsendu, Meng, Fantao, Alayash, Abdu I.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011486/
https://ncbi.nlm.nih.gov/pubmed/27642551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12103
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