Impaired Angiogenesis and Mobilization of Circulating Angiogenic Cells in HIF-1α Heterozygous-Null Mice after Burn Wounding

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that controls vascular responses to hypoxia and ischemia. In this study, mice that were heterozygous for a null allele at the locus encoding the HIF-1α subunit (HET mice) and their wild type (WT) littermates were subjected to thermal injur...

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Main Authors: Zhang, Xianjie, Liu, Lixin, Wei, Xiaofei, Tan, Yee Sun, Tong, Lana, Chang, Ryan, Ghanamah, Mohammed S., Reinblatt, Maura, Marti, Guy P., Harmon, John W., Semenza, Gregg L.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206187/
https://ncbi.nlm.nih.gov/pubmed/20163569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1524-475X.2010.00570.x
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