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Dax1 and Nanog act in parallel to stabilize mouse embryonic stem cells and induced pluripotency

Nanog expression is heterogeneous and dynamic in embryonic stem cells (ESCs). However, the mechanism for stabilizing pluripotency during the transitions between Nanog(high) and Nanog(low) states is not well understood. Here we report that Dax1 acts in parallel with Nanog to regulate mouse ESC (mESCs...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zhang, Junlei, Liu, Gaoke, Ruan, Yan, Wang, Jiali, Zhao, Ke, Wan, Ying, Liu, Bing, Zheng, Hongting, Peng, Tao, Wu, Wei, He, Ping, Hu, Fu-Quan, Jian, Rui
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Pub. Group 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205889/
https://ncbi.nlm.nih.gov/pubmed/25284313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6042
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