Invariance and restriction toward a limited set of self-antigens characterize neonatal IgM antibody repertoires and prevail in autoreactive repertoires of healthy adults.
Analysis of the reactivity of IgM with self-antigens in tissues by a quantitative immunoblotting technique showed striking invariance among newborns in the human and in the mouse. The self-reactive repertoire of IgM of adults was also markedly conserved; it comprised most anti-self reactivities that...
I tiakina i:
| I whakaputaina i: | Proc Natl Acad Sci U S A |
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| Ngā kaituhi matua: | , , , , , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
National Academy of Sciences
1995
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| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7731992/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.9.3839 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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