Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries

Specific antibody reactivities are routinely used as biomarkers, but the antibody repertoire reactivity (igome) profiles are still neglected. Here, we propose rationally designed peptide arrays as efficient probes for these system level biomarkers. Most IgM antibodies are characterized by few somati...

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Autors principals:	Anastas Pashov, Velizar Shivarov, Maya Hadzhieva, Victor Kostov, Dilyan Ferdinandov, Karen-Marie Heintz, Shina Pashova, Milena Todorova, Tchavdar Vassilev, Thomas Kieber-Emmons, Leonardo A. Meza-Zepeda, Eivind Hovig
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2019-12-01
Col·lecció:	Frontiers in Immunology
Matèries:	diagnostic phage display antibody repertoire mimotope systems immunology
Accés en línia:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02796/full
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