Proteopathic tau seeding predicts tauopathy in vivo

Transcellular propagation of protein aggregates, or proteopathic seeds, may drive the progression of neurodegenerative diseases in a prion-like manner. In tauopathies such as Alzheimer’s disease, this model predicts that tau seeds propagate pathology through the brain via cell–cell transfer in neura...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Holmes, Brandon B., Furman, Jennifer L., Mahan, Thomas E., Yamasaki, Tritia R., Mirbaha, Hilda, Eades, William C., Belaygorod, Larisa, Cairns, Nigel J., Holtzman, David M., Diamond, Marc I.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205609/
https://ncbi.nlm.nih.gov/pubmed/25261551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411649111
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki