Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

Recent experimental evidence suggests that transcellular propagation of fibrillar protein aggregates drives the progression of neurodegenerative diseases in a prion-like manner. This phenomenon is now well described in cell and animal models and involves the release of protein aggregates into the ex...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Holmes, Brandon B., DeVos, Sarah L., Kfoury, Najla, Li, Mei, Jacks, Rachel, Yanamandra, Kiran, Ouidja, Mohand O., Brodsky, Frances M., Marasa, Jayne, Bagchi, Devika P., Kotzbauer, Paul T., Miller, Timothy M., Papy-Garcia, Dulce, Diamond, Marc I.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746848/
https://ncbi.nlm.nih.gov/pubmed/23898162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301440110
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items