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Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence

Cycloaddition is an essential tool in chemical synthesis. Instead of using light or heat as a driving force, marine sponges promote cycloaddition with a more versatile but poorly understood mechanism in producing pyrrole–imidazole alkaloids sceptrin, massadine, and ageliferin. Through de novo synthe...

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Hlavní autoři: Ma, Zhiqiang, Wang, Xiaolei, Wang, Xiao, Rodriguez, Rodrigo A., Moore, Curtis E., Gao, Shuanhu, Tan, Xianghui, Ma, Yuyong, Rheingold, Arnold L., Baran, Phil S., Chen, Chuo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205478/
https://ncbi.nlm.nih.gov/pubmed/25301624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1255677
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