MUC4 Regulates Cellular Senescence in Head and Neck Squamous Cell Carcinoma (HNSCC) through p16/Rb Pathway

The limited effectiveness of therapy for patients with advanced stage Head and Neck Squamous Cell Carcinoma (HNSCC) or recurrent disease is a reflection of an incomplete understanding of the molecular basis of HNSCC pathogenesis. MUC4, a high molecular weight glycoprotein, is differentially overexpr...

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Bibliografiske detaljer
Main Authors: Macha, Muzafar A., Rachagani, Satyanarayana, Pai, Priya, Gupta, Suprit, Lydiatt, Williams M., Smith, Russell B., Johansson, Sonny L., Lele, Subodh M., Kakar, Sham S., Lee, John H., Meza, Jane, Ganti, Apar K., Jain, Maneesh, Batra, Surinder K.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205229/
https://ncbi.nlm.nih.gov/pubmed/24747969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.102
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