MUC4 Regulates Cellular Senescence in Head and Neck Squamous Cell Carcinoma (HNSCC) through p16/Rb Pathway

The limited effectiveness of therapy for patients with advanced stage Head and Neck Squamous Cell Carcinoma (HNSCC) or recurrent disease is a reflection of an incomplete understanding of the molecular basis of HNSCC pathogenesis. MUC4, a high molecular weight glycoprotein, is differentially overexpr...

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Detalhes bibliográficos
Main Authors: Macha, Muzafar A., Rachagani, Satyanarayana, Pai, Priya, Gupta, Suprit, Lydiatt, Williams M., Smith, Russell B., Johansson, Sonny L., Lele, Subodh M., Kakar, Sham S., Lee, John H., Meza, Jane, Ganti, Apar K., Jain, Maneesh, Batra, Surinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205229/
https://ncbi.nlm.nih.gov/pubmed/24747969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.102
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