Tumor necrosis factor-alpha mediates activation of NF-κB and JNK signaling cascades in retinal ganglion cells and astrocytes in opposite ways

Tumor necrosis factor-alpha (TNF) is an important mediator of the innate immune response in the retina. TNF can activate various signaling cascades, including NF-κB, nuclear factor kappa B (NF-κB) and c-Jun N-terminal kinase (JNK) pathways. The harmful role of these pathways, as well as of TNF, has...

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Bibliographic Details
Main Authors:	Dvoriantchikova, Galina, Ivanov, Dmitry
Format:	Artigo
Language:	Inglês
Published:	BlackWell Publishing Ltd 2014
Subjects:	Molecular and Synaptic Mechanisms
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4205188/ https://ncbi.nlm.nih.gov/pubmed/25160799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12710
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Tumor necrosis factor-alpha mediates activation of NF-κB and JNK signaling cascades in retinal ganglion cells and astrocytes in opposite ways

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