The TIR-domain-containing adapter inducing interferon-β-dependent signaling cascade plays a crucial role in ischemia–reperfusion-induced retinal injury, whereas the contribution of the myeloid differentiation primary response 88-dependent signaling cascade is not as pivotal

Toll-like receptor 4 (Tlr4) plays an important role in ischemia–reperfusion (IR)-induced retinal inflammation and damage. However, the role of two Tlr4-dependent signaling cascades, myeloid differentiation primary response 88 (Myd88) and TIR-domain-containing adapter inducing interferon-β (Trif), in...

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Detalhes bibliográficos
Main Authors: Dvoriantchikova, Galina, Santos, Andrea Rachelle C, Danek, Dagmara, Dvoriantchikova, Xenia, Ivanov, Dmitry
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Molecular and Synaptic Mechanisms
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122625/
https://ncbi.nlm.nih.gov/pubmed/24754835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12603
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