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A Multi-Site Study Employing High Resolution HLA Genotyping by Next Generation Sequencing
The high degree of polymorphism at HLA class I and class II loci makes high resolution HLA typing challenging. Current typing methods, including Sanger sequencing, yield ambiguous typing results due to incomplete genomic coverage and inability to set phase for HLA haplotype determination. The 454 Li...
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| Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205124/ https://ncbi.nlm.nih.gov/pubmed/21299525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-0039.2010.01606.x |
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