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High-resolution, high-throughput HLA genotyping by next-generation sequencing

The human leukocyte antigen (HLA) class I and class II loci are the most polymorphic genes in the human genome. Hematopoietic stem cell transplantation requires allele-level HLA typing at multiple loci to select the best matched unrelated donors for recipient patients. In current methods for HLA typ...

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Detalhes bibliográficos
Main Authors: Bentley, G., Higuchi, R., Hoglund, B., Goodridge, D., Sayer, D., Trachtenberg, E. A., Erlich, H. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205125/
https://ncbi.nlm.nih.gov/pubmed/19845894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-0039.2009.01345.x
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