Phospholipase C δ-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells

BACKGROUND: The expression of the rodent phosphoinositide-specific phospholipase C δ-4 (PLCδ4) has been found to be elevated upon mitogenic stimulation and expression analysis have linked the upregulation of PLCδ4 expression with rapid proliferation in certain rat transformed cell lines. The human h...

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Bibliographic Details

Published in:	Mol Cancer
Main Authors:	Leung, David W, Tompkins, Chris, Brewer, Jim, Ball, Alexey, Coon, Mike, Morris, Valerie, Waggoner, David, Singer, Jack W
Format:	Artigo
Language:	Inglês
Published:	BMC 2004
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15140260/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1476-4598-3-15
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