Phospholipase C δ-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells

BACKGROUND: The expression of the rodent phosphoinositide-specific phospholipase C δ-4 (PLCδ4) has been found to be elevated upon mitogenic stimulation and expression analysis have linked the upregulation of PLCδ4 expression with rapid proliferation in certain rat transformed cell lines. The human h...

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Detalhes bibliográficos

Publicado no:	Mol Cancer
Principais autores:	Leung, David W, Tompkins, Chris, Brewer, Jim, Ball, Alexey, Coon, Mike, Morris, Valerie, Waggoner, David, Singer, Jack W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2004
Assuntos:	Research
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15140260/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1476-4598-3-15
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