Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice

The t(12;21) translocation, which generates the TEL-AML1 (ETV6-RUNX1) fusion gene, is the most common structural chromosome change in childhood cancer and is exclusively associated with the common B cell precursor subset of acute lymphoblastic leukemia (ALL). Evidence suggests that the translocation...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Tsuzuki, Shinobu, Seto, Masao, Greaves, Mel, Enver, Tariq
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155899/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402063101
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