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Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice

The t(12;21) translocation, which generates the TEL-AML1 (ETV6-RUNX1) fusion gene, is the most common structural chromosome change in childhood cancer and is exclusively associated with the common B cell precursor subset of acute lymphoblastic leukemia (ALL). Evidence suggests that the translocation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tsuzuki, Shinobu, Seto, Masao, Greaves, Mel, Enver, Tariq
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC420413/
https://ncbi.nlm.nih.gov/pubmed/15155899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402063101
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