Transcriptome-wide characterization of the eIF4A signature highlights plasticity in translation regulation

BACKGROUND: Protein synthesis is tightly regulated and alterations to translation are characteristic of many cancers. Translation regulation is largely exerted at initiation through the eukaryotic translation initiation factor 4 F (eIF4F). eIF4F is pivotal for oncogenic signaling as it integrates mi...

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Detaylı Bibliyografya
Asıl Yazarlar: Rubio, Claudia A, Weisburd, Benjamin, Holderfield, Matthew, Arias, Carolina, Fang, Eric, DeRisi, Joseph L, Fanidi, Abdallah
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203936/
https://ncbi.nlm.nih.gov/pubmed/25273840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0476-1
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