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Transcriptome-wide characterization of the eIF4A signature highlights plasticity in translation regulation
BACKGROUND: Protein synthesis is tightly regulated and alterations to translation are characteristic of many cancers. Translation regulation is largely exerted at initiation through the eukaryotic translation initiation factor 4 F (eIF4F). eIF4F is pivotal for oncogenic signaling as it integrates mi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4203936/ https://ncbi.nlm.nih.gov/pubmed/25273840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0476-1 |
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