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The dynamic processivity of the T4 DNA polymerase during replication

The polymerase (gp43) processivity during T4 replisome mediated DNA replication has been investigated. The size of the Okazaki fragments remains constant over a wide range of polymerase concentrations. A dissociation rate constant of ≈0.0013 sec(-1) was measured for the polymerases from both strands...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Jingsong, Zhuang, Zhihao, Roccasecca, Rosa Maria, Trakselis, Michael A., Benkovic, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC420387/
https://ncbi.nlm.nih.gov/pubmed/15148377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402625101
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