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Itraconazole suppresses the growth of glioblastoma through induction of autophagy: Involvement of abnormal cholesterol trafficking

Glioblastoma is one of the most aggressive human cancers with poor prognosis, and therefore a critical need exists for novel therapeutic strategies for management of glioblastoma patients. Itraconazole, a traditional antifungal drug, has been identified as a novel potential anticancer agent due to i...

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Detalhes bibliográficos
Main Authors: Liu, Rui, Li, Jingyi, Zhang, Tao, Zou, Linzhi, Chen, Yi, Wang, Kui, Lei, Yunlong, Yuan, Kefei, Li, Yi, Lan, Jiang, Cheng, Lin, Xie, Na, Xiang, Rong, Nice, Edouard C, Huang, Canhua, Wei, Yuquan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203550/
https://ncbi.nlm.nih.gov/pubmed/24905460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.28912
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