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Pyrvinium targets autophagy addiction to promote cancer cell death
Autophagy is a cellular catabolic process by which long-lived proteins and damaged organelles are degradated by lysosomes. Activation of autophagy is an important survival mechanism that protects cancer cells from various stresses, including anticancer agents. Recent studies indicate that pyrvinium...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674351/ https://ncbi.nlm.nih.gov/pubmed/23640456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.142 |
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