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Pyrvinium targets autophagy addiction to promote cancer cell death

Autophagy is a cellular catabolic process by which long-lived proteins and damaged organelles are degradated by lysosomes. Activation of autophagy is an important survival mechanism that protects cancer cells from various stresses, including anticancer agents. Recent studies indicate that pyrvinium...

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Detalhes bibliográficos
Main Authors: Deng, Longfei, Lei, Yunlong, Liu, Rui, Li, Jingyi, Yuan, Kefei, Li, Yi, Chen, Yi, Liu, Yi, Lu, You, Edwards III, Carl K, Huang, Canhua, Wei, Yuquan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674351/
https://ncbi.nlm.nih.gov/pubmed/23640456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.142
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