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Pyrvinium targets autophagy addiction to promote cancer cell death

Autophagy is a cellular catabolic process by which long-lived proteins and damaged organelles are degradated by lysosomes. Activation of autophagy is an important survival mechanism that protects cancer cells from various stresses, including anticancer agents. Recent studies indicate that pyrvinium...

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Détails bibliographiques
Auteurs principaux: Deng, Longfei, Lei, Yunlong, Liu, Rui, Li, Jingyi, Yuan, Kefei, Li, Yi, Chen, Yi, Liu, Yi, Lu, You, Edwards III, Carl K, Huang, Canhua, Wei, Yuquan
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674351/
https://ncbi.nlm.nih.gov/pubmed/23640456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.142
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