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Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability
Nonhomologous end joining (NHEJ) and homologous recombination (HR) represent the two major pathways of DNA double-strand break (DSB) repair in eukaryotic cells. NHEJ repairs DSBs by ligation of cognate broken ends irrespective of homologous flanking sequences, whereas HR repairs DSBs using an undama...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC420354/ https://ncbi.nlm.nih.gov/pubmed/15175260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1204304 |
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