Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability

Nonhomologous end joining (NHEJ) and homologous recombination (HR) represent the two major pathways of DNA double-strand break (DSB) repair in eukaryotic cells. NHEJ repairs DSBs by ligation of cognate broken ends irrespective of homologous flanking sequences, whereas HR repairs DSBs using an undama...

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Pubblicato in:	Genes Dev
Autori principali:	Mills, Kevin D., Ferguson, David O., Essers, Jeroen, Eckersdorff, Mark, Kanaar, Roland, Alt, Frederick W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2004
Soggetti:	Research Papers
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15175260/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1204304
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