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Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells

In mammalian cells, repair of DNA double-strand breaks (DSBs) occurs by both homologous and non-homologous mechanisms. By definition, homologous recombination requires a template with sufficient sequence identity to the damaged molecule in order to direct repair. We now show that the sister chromati...

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Détails bibliographiques
Auteurs principaux: Johnson, Roger D., Jasin, Maria
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC313931/
https://ncbi.nlm.nih.gov/pubmed/10880452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3398
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