Nuclear surveillance and degradation of hypomodified initiator tRNA(Met) in S. cerevisiae

The tRNA m(1)A58 methyltransferase is composed of two subunits encoded by the essential genes TRM6 and TRM61 (formerly GCD10 and GCD14). The trm6-504 mutation results in a defective m(1)A methyltransferase (Mtase) and a temperature-sensitive growth phenotype that is attributable to the absence of m(...

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Pubblicato in:	Genes Dev
Autori principali:	Kadaba, Sujatha, Krueger, Anna, Trice, Tamyra, Krecic, Annette M., Hinnebusch, Alan G., Anderson, James
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2004
Soggetti:	Research Papers
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15145828/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1183804
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