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Nuclear surveillance and degradation of hypomodified initiator tRNA(Met) in S. cerevisiae
The tRNA m(1)A58 methyltransferase is composed of two subunits encoded by the essential genes TRM6 and TRM61 (formerly GCD10 and GCD14). The trm6-504 mutation results in a defective m(1)A methyltransferase (Mtase) and a temperature-sensitive growth phenotype that is attributable to the absence of m(...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC420349/ https://ncbi.nlm.nih.gov/pubmed/15145828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1183804 |
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