Nuclear surveillance and degradation of hypomodified initiator tRNA(Met) in S. cerevisiae

The tRNA m(1)A58 methyltransferase is composed of two subunits encoded by the essential genes TRM6 and TRM61 (formerly GCD10 and GCD14). The trm6-504 mutation results in a defective m(1)A methyltransferase (Mtase) and a temperature-sensitive growth phenotype that is attributable to the absence of m(...

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書誌詳細

出版年:	Genes Dev
主要な著者:	Kadaba, Sujatha, Krueger, Anna, Trice, Tamyra, Krecic, Annette M., Hinnebusch, Alan G., Anderson, James
フォーマット:	Artigo
言語:	Inglês
出版事項:	Cold Spring Harbor Laboratory Press 2004
主題:	Research Papers
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15145828/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1183804
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