Nuclear surveillance and degradation of hypomodified initiator tRNA(Met) in S. cerevisiae

The tRNA m(1)A58 methyltransferase is composed of two subunits encoded by the essential genes TRM6 and TRM61 (formerly GCD10 and GCD14). The trm6-504 mutation results in a defective m(1)A methyltransferase (Mtase) and a temperature-sensitive growth phenotype that is attributable to the absence of m(...

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Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Kadaba, Sujatha, Krueger, Anna, Trice, Tamyra, Krecic, Annette M., Hinnebusch, Alan G., Anderson, James
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 2004
Fag:	Research Papers
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15145828/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1183804
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