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B Cells Regulate CD4+ T cell Responses to Papain Following BCR-Independent Papain Uptake

Papain, a cysteine protease allergen with inherent adjuvant activity, induces potent IL4 expression by T cells in the popliteal lymph nodes (PLN) of mice following footpad immunization. Here we identify a novel, non-BCR mediated capacity for B cells to rapidly bind and internalize papain. B cells su...

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Detalhes bibliográficos
Main Authors: Dwyer, Daniel F., Woodruff, Matthew C., Carroll, Michael C., Austen, K. Frank, Gurish, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203309/
https://ncbi.nlm.nih.gov/pubmed/24928991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303247
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