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Agammaglobulinemia associated with BCR(−) B cells and enhanced expression of CD19
Expression of a BCR is critical for B-cell development and survival. We have identified 4 patients with agammaglobulinemia and markedly reduced but detectable B cells in the peripheral circulation. These B cells have an unusual phenotype characterized by increased expression of CD19 but no BCR. The...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158715/ https://ncbi.nlm.nih.gov/pubmed/21693761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-330472 |
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