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Kinetic analysis of antagonist-occupied adenosine-A(3) receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism
In our previous work, using a fluorescent adenosine-A(3) receptor (A(3)AR) agonist and fluorescence correlation spectroscopy (FCS), we demonstrated high-affinity labeling of the active receptor (R*) conformation. In the current study, we used a fluorescent A(3)AR antagonist (CA200645) to study the b...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Federation of American Societies for Experimental Biology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4202110/ https://ncbi.nlm.nih.gov/pubmed/24970394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-247270 |
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