Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease

Extracellular α-synuclein is important in the pathogenesis of Parkinson disease (PD) and also as a potential biomarker when tested in the cerebrospinal fluid (CSF). The performance of blood plasma or serum α-synuclein as a biomarker has been found to be inconsistent and generally ineffective, largel...

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Detalhes bibliográficos
Main Authors: Shi, Min, Liu, Changqin, Cook, Travis J., Bullock, Kristin M., Zhao, Yanchun, Ginghina, Carmen, Li, Yanfei, Aro, Patrick, Dator, Romel, He, Chunmei, Hipp, Michael J., Zabetian, Cyrus P., Peskind, Elaine R., Hu, Shu-Ching, Quinn, Joseph F., Galasko, Douglas R., Banks, William A., Zhang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201967/
https://ncbi.nlm.nih.gov/pubmed/24997849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1314-y
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