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An alpha-synuclein MRM assay with diagnostic potential for Parkinson’s disease and monitoring disease progression

AIM: The alpha-synuclein (α-syn) level in human cerebrospinal fluid (CSF), as measured by immunoassays, is promising as a Parkinson’s disease (PD) biomarker. However, the levels of total α-syn are inconsistent among studies with large cohorts and different measurement platforms. Total α-syn level al...

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Bibliografske podrobnosti
izdano v:Proteomics Clin Appl
Main Authors: Yang, Li, Stewart, Tessandra, Shi, Min, Pottiez, Gwenael, Dator, Romel, Wu, Rui, Aro, Patrick, Schuster, Robert J., Ginghina, Carmen, Pan, Catherine, Gao, Yuqian, Qian, Weijun, Zabetian, Cyrus P., Hu, Shu-Ching, Quinn, Joseph F., Zhang, Jing
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540649/
https://ncbi.nlm.nih.gov/pubmed/28319654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201700045
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