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CYCLIN A2 AND ITS ASSOCIATED KINASE ACTIVITY ARE REQUIRED FOR OPTIMAL INDUCTION OF PROGESTERONE RECEPTOR TARGET GENES IN BREAST CANCER CELLS

A role for the cell cycle protein cyclin A2 in regulating progesterone receptor (PR) activity is emerging. This study investigates the role of cyclin A2 in regulating endogenous PR activity in T47D breast cancer cells by depleting cyclin A2 expression and measuring PR target genes using q-RT-PCR. Ta...

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Détails bibliographiques
Auteurs principaux: Moore, Nicole L., Edwards, Dean P., Weigel, Nancy L.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201666/
https://ncbi.nlm.nih.gov/pubmed/25220500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2014.09.009
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