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BMP Signaling in Astrocytes Downregulates EGFR to Modulate Survival and Maturation

Astrocytes constitute a major cell population in the brain with a myriad of essential functions, yet we know remarkably little about the signaling pathways and mechanisms that direct astrocyte maturation. To explore the signals regulating astrocyte development, we prospectively purified and cultured...

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Autors principals: Scholze, Anja R., Foo, Lynette C., Mulinyawe, Sara, Barres, Ben A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201562/
https://ncbi.nlm.nih.gov/pubmed/25330173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110668
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