NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes

[Image: see text] The small-molecule probes STF-31 and its analogue compound 146 were discovered while searching for compounds that kill VHL-deficient renal cell carcinoma cell lines selectively and have been reported to act via direct inhibition of the glucose transporter GLUT1. We profiled the sen...

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Autori principali: Adams, Drew J., Ito, Daisuke, Rees, Matthew G., Seashore-Ludlow, Brinton, Puyang, Xiaoling, Ramos, Alex H., Cheah, Jaime H., Clemons, Paul A., Warmuth, Markus, Zhu, Ping, Shamji, Alykhan F., Schreiber, Stuart L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201331/
https://ncbi.nlm.nih.gov/pubmed/25058389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500347p
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