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A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma
[Image: see text] Post-translational modifications of histones alter chromatin structure and play key roles in gene expression and specification of cell states. Small molecules that target chromatin-modifying enzymes selectively are useful as probes and have promise as therapeutics, although very fe...
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| Główni autorzy: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical
Society
2012
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401036/ https://ncbi.nlm.nih.gov/pubmed/22536950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300139y |
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