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Computational Analyses Connect Small-Molecule Sensitivity to Cellular Features Using Large Panels of Cancer Cell Lines

We recently pioneered several analyses of small-molecule sensitivity data collected from large-scale perturbation of hundreds of cancer cell lines with hundreds of small molecules, with cell viability measured as a readout of compound sensitivity. We performed these studies using cancer cell lines p...

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Veröffentlicht in:Methods Mol Biol
Hauptverfasser: Rees, Matthew G., Seashore-Ludlow, Brinton, Clemons, Paul A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563933/
https://ncbi.nlm.nih.gov/pubmed/30519951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8891-4_14
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