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Platinum-RNA Modifications Following Drug Treatment in S. cerevisiae Identified by Click Chemistry and Enzymatic Mapping

[Image: see text] With the importance of RNA-based regulatory pathways, the potential for targeting noncoding and coding RNAs by small molecule therapeutics is of great interest. Platinum(II) complexes including cisplatin (cis-diamminedichloroplatinum(II)) are widely prescribed anticancer compounds...

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Bibliografski detalji
Glavni autori: Osborn, Maire F., White, Jonathan D., Haley, Michael M., DeRose, Victoria J.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201330/
https://ncbi.nlm.nih.gov/pubmed/25055168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500395z
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