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Picazoplatin, an Azide-Containing Platinum(II) Derivative for Target Analysis by Click Chemistry

Despite the broad use of platinum-based chemotherapeutics, identification of their full range of cellular targets remains a significant challenge. In order to identify, visualize, and isolate cellular targets of Pt(II) complexes, we have modified the chemotherapeutic drug picoplatin with an azide mo...

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Detalhes bibliográficos
Main Authors: White, Jonathan D., Osborn, Maire F., Moghaddam, Alan D., Guzman, Lindsay E., Haley, Michael M., DeRose, Victoria J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130293/
https://ncbi.nlm.nih.gov/pubmed/23879391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja402453k
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