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Biochemical Stabilization of Glucagon at Alkaline pH

Background: For patients with type 1 diabetes mellitus, a bihormonal artificial endocrine pancreas system utilizing glucagon and insulin has been found to stabilize glycemic control. However, commercially available formulations of glucagon cannot currently be used in such systems because of physical...

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Bibliographic Details
Main Authors: Caputo, Nicholas, Jackson, Melanie A., Castle, Jessica R., El Youssef, Joseph, Bakhtiani, Parkash A., Bergstrom, Colin P., Carroll, Julie M., Breen, Matthew E., Leonard, Gerald L., David, Larry L., Roberts, Charles T., Ward, W. Kenneth
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201307/
https://ncbi.nlm.nih.gov/pubmed/24968220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dia.2014.0047
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