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Stable liquid glucagon formulations for rescue treatment and bi-hormonal closed-loop pancreas
Small doses of glucagon given subcutaneously in the research setting by an automated system prevent most cases of hypoglycemia in persons with diabetes. However, glucagon is very unstable and cannot be kept in a portable pump. Glucagon rapidly forms amyloid fibrils, even within the first day after r...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970213/ https://ncbi.nlm.nih.gov/pubmed/22972416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-012-0320-5 |
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