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A Novel, Stable, Aqueous Glucagon Formulation Using Ferulic Acid as an Excipient
BACKGROUND: Commercial glucagon is unstable due to aggregation and degradation. In closed-loop studies, it must be reconstituted frequently. For use in a portable pump for 3 days, a more stable preparation is required. At alkaline pH, curcumin inhibited glucagon aggregation. However, curcumin is not...
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| Publicado no: | J Diabetes Sci Technol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4495527/ https://ncbi.nlm.nih.gov/pubmed/25253164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1932296814552476 |
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