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Efavirenz Induces Neuronal Autophagy and Mitochondrial Alterations

Efavirenz (EFV) is a non-nucleoside reverse-transcriptase inhibitor in wide use for the treatment of human immunodeficiency virus infection. Although EFV is generally well tolerated, neuropsychiatric toxicity has been well documented. The toxic effects of EFV in hepatocytes and keratinocytes have be...

詳細記述

保存先:
書誌詳細
主要な著者: Purnell, Phillip R., Fox, Howard S.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201278/
https://ncbi.nlm.nih.gov/pubmed/25161171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.217869
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