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Efavirenz Induces Neuronal Autophagy and Mitochondrial Alterations

Efavirenz (EFV) is a non-nucleoside reverse-transcriptase inhibitor in wide use for the treatment of human immunodeficiency virus infection. Although EFV is generally well tolerated, neuropsychiatric toxicity has been well documented. The toxic effects of EFV in hepatocytes and keratinocytes have be...

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Detalhes bibliográficos
Main Authors: Purnell, Phillip R., Fox, Howard S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201278/
https://ncbi.nlm.nih.gov/pubmed/25161171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.217869
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