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Early expression of Parkinson’s disease-related mitochondrial abnormalities in PINK1 knockout rats

PTEN-induced kinase 1 (PINK1) mutations are responsible for an autosomal recessive, familial form of Parkinson’s disease. PINK1 protein is a Ser/Thr kinase localized to the mitochondrial membrane and is involved in many processes including mitochondrial trafficking, mitophagy, and proteasomal functi...

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Publicat a:Mol Neurobiol
Autors principals: Villeneuve, Lance M., Purnell, Phillip R., Boska, Michael D., Fox, Howard S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442772/
https://ncbi.nlm.nih.gov/pubmed/25421206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8927-y
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